PLOS Clinical Trials was launched in May 2006, and devoted to publishing the results of all correctly conducted and reported clinical trials, irrespective of outcome. The journal was merged in August 2007 with PLOS ONE, which has now taken over the editorial mission of PLOS Clinical Trials. All articles previously published in PLOS Clinical Trials can be browsed and searched via this site, using the article links on the homepage or the search bar above. PLOS Clinical Trials is closed to new submissions, but authors can submit their work to other PLOS journals for which their paper is in scope. All PLOS Clinical Trials articles remain archived in PubMed Central and indexed by PubMed.